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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNB2L1
All Species:
39.7
Human Site:
Y228
Identified Species:
58.22
UniProt:
P63244
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P63244
NP_006089.1
317
35077
Y228
L
N
E
G
K
H
L
Y
T
L
D
G
G
D
I
Chimpanzee
Pan troglodytes
Q5IS43
410
46712
E271
A
T
K
E
C
K
A
E
L
R
E
H
E
H
V
Rhesus Macaque
Macaca mulatta
XP_001105066
393
42789
Y304
L
N
E
G
K
H
L
Y
T
L
D
G
G
D
I
Dog
Lupus familis
XP_537934
316
34871
Y227
L
N
E
G
K
H
L
Y
T
L
D
G
G
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHD1
476
53485
H317
K
R
N
L
K
R
L
H
F
E
A
S
P
H
L
Rat
Rattus norvegicus
P63245
317
35058
Y228
L
N
E
G
K
H
L
Y
T
L
D
G
G
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511303
428
47737
Y339
L
N
E
G
K
H
L
Y
T
L
D
G
G
D
I
Chicken
Gallus gallus
Q9PTR5
410
46646
E271
A
T
K
E
C
K
A
E
L
R
E
H
E
H
V
Frog
Xenopus laevis
Q6DE72
410
46731
T292
A
P
E
S
S
Y
S
T
I
S
D
A
T
G
S
Zebra Danio
Brachydanio rerio
O42248
317
35104
Y228
L
N
E
G
K
H
L
Y
T
L
D
G
G
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O18640
318
35599
Y229
L
N
D
G
K
N
L
Y
T
L
E
H
N
D
I
Honey Bee
Apis mellifera
XP_392962
317
35737
H228
L
N
D
G
K
H
L
H
T
L
D
H
N
D
I
Nematode Worm
Caenorhab. elegans
Q21215
325
35812
Y234
L
N
E
G
K
H
L
Y
T
L
P
G
N
D
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O24456
327
35729
Y230
L
A
E
G
K
K
L
Y
S
L
E
A
N
S
V
Baker's Yeast
Sacchar. cerevisiae
P38011
319
34787
Y232
L
A
A
K
K
A
M
Y
T
L
S
A
Q
D
E
Red Bread Mold
Neurospora crassa
Q01369
316
35112
Y228
L
N
E
S
K
H
L
Y
S
L
N
A
N
D
E
Conservation
Percent
Protein Identity:
100
23.4
80.6
99.3
N.A.
23.9
100
N.A.
74
23.6
23.8
95.5
N.A.
76.4
79.5
71.3
N.A.
Protein Similarity:
100
39.5
80.6
99.3
N.A.
37.1
100
N.A.
74
39.5
39.2
99.6
N.A.
86.4
88.3
82.4
N.A.
P-Site Identity:
100
0
100
100
N.A.
13.3
100
N.A.
100
0
13.3
93.3
N.A.
66.6
73.3
80
N.A.
P-Site Similarity:
100
20
100
100
N.A.
26.6
100
N.A.
100
20
20
93.3
N.A.
86.6
86.6
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
65.4
52.9
70.6
Protein Similarity:
N.A.
N.A.
N.A.
77.3
70.2
83.6
P-Site Identity:
N.A.
N.A.
N.A.
46.6
40
60
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
46.6
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
13
7
0
0
7
13
0
0
0
7
25
0
0
0
% A
% Cys:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
0
0
0
0
0
0
50
0
0
69
0
% D
% Glu:
0
0
63
13
0
0
0
13
0
7
25
0
13
0
13
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
0
0
0
63
0
0
0
0
0
0
0
44
38
7
0
% G
% His:
0
0
0
0
0
57
0
13
0
0
0
25
0
19
0
% H
% Ile:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
44
% I
% Lys:
7
0
13
7
82
19
0
0
0
0
0
0
0
0
0
% K
% Leu:
75
0
0
7
0
0
75
0
13
75
0
0
0
0
7
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
63
7
0
0
7
0
0
0
0
7
0
32
0
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
7
0
7
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
7
0
0
0
7
0
0
0
13
0
0
0
0
0
% R
% Ser:
0
0
0
13
7
0
7
0
13
7
7
7
0
7
7
% S
% Thr:
0
13
0
0
0
0
0
7
63
0
0
0
7
0
7
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
69
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _